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Study details
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KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer

Christian Hinrichs
NCT IDNCT05483491ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

30

Study length

about 6.3 years

Ages

18+

Locations

2 sites in NJ

What this study is about

This trial is testing the safety of KK-LC-1 TCR-T cells in people with advanced cancers that express KK-LC-1. Participants will receive a treatment regimen including KK-LC-1 TCR-T cells, aldesleukin, and a conditioning regimen. The goal is to determine the maximum dose of this treatment and assess its effects on the body.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive KK-LC-1 TCR-T cells
  • 2.Take Aldesleukin

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

aldesleukin

Endpoints

Primary: Maximum tolerated dose (MTD) of KK-LC-1 TCR-T cells

Secondary: Adverse events of KK-LC-1 TCR T cells, Tumor response rate

Body systems

Oncology