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Study details
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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

VA Office of Research and Development
NCT IDNCT05486572ClinicalTrials.gov data as of Apr 2026
Target enrollment

4,700

Study length

about 7.8 years

Ages

18–75

Locations

17 sites in CA, CO, CT +10

What this study is about

This trial is testing whether an abbreviated MRI screening with blood tests, or abdominal ultrasound screening with blood tests, can help detect liver cancer earlier in people with cirrhosis. The goal is to see if this approach leads to a reduction in deaths from liver cancer.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Undergo Abbreviated Magnetic Resonance Imaging with serum AFP
  • 2.Undergo Abdominal Ultrasound Screening with serum AFP

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Overall Survival

Body systems

Gastroenterology