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Study details
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The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

Temple University
NCT IDNCT05499507ClinicalTrials.gov data as of Apr 2026
Target enrollment

432

Study length

about 5.9 years

Ages

18+

Sex

Female only

Locations

1 site in PA

What this study is about

This trial is testing two different ways to help Black women with high blood pressure and/or obesity reduce their risk of heart disease during pregnancy. One approach focuses on individual behaviors like healthy eating and exercise, while the other addresses psychosocial factors such as depression, social isolation, and racism that can also impact heart health. The goal is to see which approach works best at improving heart health outcomes for Black women.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in COH
  • 2.Participate in COH+

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change in blood pressure at 12-months postpartum., Change in blood pressure at 6-weeks postpartum., Change in body weight at 12-months postpartum., Change in body weight at 6-weeks postpartum.

Secondary: Blood pressure control at 12-months postpartum for patients with hypertension at baseline., Blood pressure control at 6-weeks postpartum for patients with hypertension (HTN) at baseline.

Body systems

Endocrinology, Cardiology / Heart