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Study details
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A Study Assessing KB407 for the Treatment of Cystic Fibrosis

Krystal Biotech, Inc.
NCT IDNCT05504837ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

12

Study length

about 2.6 years

Ages

18+

Locations

5 sites in FL, IL, NC +1

What this study is about

Researchers are testing a treatment called KB407, given through nebulization, to see if it's safe and well-tolerated in adults with cystic fibrosis. The trial will last approximately 946 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive KB407 (Nebulization)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: To evaluate safety and tolerability of KB407 based upon assessment of adverse events (frequency, severity, relatedness), and changes from baseline in physical examinations, vital signs, ECG, and clinical laboratory test results

Secondary: To evaluate the effects of KB407 on pulmonary function, as measured by change from baseline in absolute and percent predicted FEV1

Body systems

Respiratory