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Study details
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Overcoming Nicotine Dependence to Enable Quitting

Rush University Medical Center
NCT IDNCT05513872ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

780

Study length

about 4.4 years

Ages

18+

Locations

1 site in IL

What this study is about

This trial is testing whether practice quitting counseling, nicotine replacement therapy (NRT), or motivational interviewing (MI) counseling can help people who want to quit smoking. The goal is to determine which approach is most effective at helping smokers try not smoking for a short time.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Motivational Interviewing (MI) Counseling
  • 2.Participate in Practice Quitting (PQ) Counseling
  • 3.Take Nicotine Replacement Therapy (NRT) Sampling

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

NERVOUS SYSTEM

Drug routes

oral (Oral Lozenge)