Study details
Enrolling now
A Phase I Intravesical PPM Therapy for NMIBC
VA Office of Research and Development
NCT IDNCT05519241ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
29
Study length
about 3.9 years
Ages
18+
Locations
1 site in MA
What this study is about
This trial is testing a new treatment called PLZ4-coated paclitaxel-loaded micelles (PPM) in people with non-muscle-invasive bladder cancer. The goal is to determine the safety and effectiveness of PPM, which is a drug delivered directly into the bladder.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take PLZ4-coated paclitaxel-loaded micelles (PPM)
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Injection / IV
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
chemotherapy (Taxane chemotherapy; stabilizes microtubules)
Drug routes
infusion
Endpoints
Primary: adverse events
Secondary: complete response rate
Body systems
Oncology