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Study details
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Low Dose Naltrexone for Pain in Patients With HIV

Emory University
NCT IDNCT05537935ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

60

Study length

about 3.7 years

Ages

18–75

Locations

3 sites in GA

What this study is about

Researchers are testing whether low dose naltrexone can help reduce pain in people with HIV/AIDS. The trial will monitor CD4 counts as part of routine care to see if the medication improves immune function and reduces symptoms. This could be a new way to manage pain for people living with HIV.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Low Dose Naltrexone

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

NERVOUS SYSTEM

Drug routes

injection (Injection)

Endpoints

Primary: Changes in Numerical Pain Score

Secondary: Changes in Average pain Score, Changes in PROMIS pain Score

Body systems

Immune, Infectious