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Study details
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Depression, Aging, Stress and Heart Health Study

University of North Carolina, Chapel Hill
NCT IDNCT05570721ClinicalTrials.gov data as of Apr 2026
Target enrollment

30

Study length

about 3.6 years

Ages

44–55

Sex

Female only

Locations

1 site in NC

What this study is about

This trial is testing if a stress test called the Trier Social Stress Test can help understand how depression, aging, stress, and heart health are linked in women during menopause. The goal is to see if disrupting certain stress pathways might reduce the risk of heart disease.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Trier Social Stress Test

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Change in heart rate variability defined as the root mean square of successive differences (RMSSD) between normal heartbeats in ms in response to the stress task., Heart rate variability defined as the root mean square of successive differences (RMSSD) between normal heartbeats in ms values at rest (before the stress task).

Procedures

diagnostic

Body systems

Psychiatry / Mental Health, Reproductive Health, Cardiology / Heart