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Study details
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Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Trial

University of Michigan
NCT IDNCT05574400ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

250

Study length

about 3.3 years

Ages

70+

Locations

1 site in MI

What this study is about

Researchers are testing if caffeine helps reduce delirium after surgery. The trial will give participants either caffeine or a placebo along with dextrose water. It aims to see if caffeine can lower the risk of postoperative delirium.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Caffeine citrate
  • 2.Take Dextrose Water

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Central Nervous System Agent (Enzyme Inhibitors)

Drug routes

injection, intravenous

Body systems

Neurology