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Study details
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Pyridostigmine for the Treatment of Constipation in Parkinson Disease

University of Vermont Medical Center
NCT IDNCT05603715ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Ages

18+

Locations

1 site in VT

What this study is about

This Phase 2 study is testing Pyridostigmine Bromide in people with constipation.

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Antimyasthenic Agents (Cholinesterase Inhibitors)

Drug routes

injection

Endpoints

Secondary: Changes from Baseline to the End of Study Visit in Beck Depression Inventory-II (BDI-II), Changes from Baseline to the End of Study Visit in the Gastrointestinal Dysfunction Scale in Parkinson's Disease (GIDS-PD), Changes from Baseline to the End of Study Visit in the MDS-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Parts I-IV, Number of adverse events and serious adverse events that occur during the trial

Body systems

Neurology, Gastroenterology