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Study details
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Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

National Cancer Institute (NCI)
NCT IDNCT05616650ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

42

Study length

about 5.1 years

Ages

18–120

Sex

Male only

Locations

1 site in MD

What this study is about

This trial is testing focal therapy with SBRT to see how people with early prostate cancer respond. Participants will receive radiation treatment using small gold seeds and follow-up scans and blood tests for two years.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Stereotactic Body Radiation Therapy
  • 2.Take 18F-DCFPyL

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

piflufolastat (18F)

Endpoints

Primary: Pathologic complete response rate

Secondary: Longitudinal quality of life (QoL), Toxicity profile

Procedures

radiation

Body systems

Oncology