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Study details
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Anti-Inflammatory Drugs and Prostate-Specific Antigen Test

Albany Medical College
NCT IDNCT05629494ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

198

Study length

about 4.2 years

Ages

18–80

Sex

Male only

Locations

3 sites in IL, NY, PA

What this study is about

Researchers are testing whether taking ibuprofen, a common anti-inflammatory drug, can lower PSA levels in men with elevated PSA. The trial will involve approximately 200 adult men who have an elevated PSA level. Participants will take ibuprofen three times daily for about 15 months.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.PSA test
  • 2.Take Ibuprofen 400 mg, TID

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ibuprofen

Drug routes

oral

Endpoints

Secondary: Changes in voiding symptoms as measured by the International Prostate Symptom Score

Procedures

diagnostic

Body systems

Reproductive Health, Oncology