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Study details
Enrolling now

Tocilizumab for Acute Chest Syndrome

University of Chicago
NCT IDNCT05640271ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

200

Study length

about 3.8 years

Ages

12+

Locations

1 site in IL

What this study is about

This trial is testing if a low dose of tocilizumab, a medication that blocks interleukin-6 (IL-6), can help treat acute chest syndrome in people with sickle cell disease. The goal is to see how this treatment affects oxygen levels, clinical outcomes, and lab results for patients hospitalized with acute chest syndrome.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Tocilizumab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

tocilizumab (Monoclonal antibody; blocks IL-6 receptor to reduce inflammation)

Drug routes

infusion

Endpoints

Secondary: Length of stay, Mortality rate, Readmission rate