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Study details
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CTX112 Trial

CRISPR Therapeutics AG
NCT IDNCT05643742ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

120

Study length

about 7 years

Ages

18+

Locations

4 sites in KS, MO, TX +1

What this study is about

This trial is testing the safety and effectiveness of CTX112 in people with relapsed or refractory B-cell malignancies. CTX112 is a type of immunotherapy that uses modified T cells to target cancer cells.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive CTX112

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Phase 1 (Dose Escalation): Incidence of adverse events, defined as dose-limiting toxicities, Phase 2 (Cohort Expansion): Objective response rate

Secondary: Duration of Response, Overall Survival, Progression Free Survival

Body systems

Oncology