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Study details
Enrolling now

Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

Columbia University
NCT IDNCT05655325ClinicalTrials.gov data as of Apr 2026
Target enrollment

144

Study length

about 2.6 years

Ages

55+

Locations

1 site in NY

What this study is about

Researchers are testing if 6 months of home-based walking improves memory, brain structure, and function in older adults with chronic kidney disease and mild cognitive impairment compared to health education. The trial will last for about a year.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Attention control
  • 2.Participate in Home-based walking exercise

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Change from baseline to 6-months in cerebral blood flow., Change from baseline to 6-months in hippocampal volume, Change from baseline to 6-months in white matter fractional anisotropy., Change from baseline to 6-months in white matter mean diffusivity.

Body systems

Neurology, Renal