Study details
Enrolling now
A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults With HR+ Breast Cancer and Other Select Solid Tumors
Totus Medicines
NCT IDNCT05683418ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
241
Study length
about 3.9 years
Ages
18+
Locations
9 sites in CA, IL, MA +4
What this study is about
This trial is testing a treatment called TOS-358 for adults with certain types of cancer. The goal is to see if it's safe and how well it works at different doses, as well as determine the maximum tolerated dose.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take TOS-358
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Primary: Incidence and severity of adverse events (AEs) and specific laboratory abnormalities graded according to NCI CTCAE v5
Body systems
Oncology