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Study details
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A Study of Letermovir to Prevent Cytomegalovirus Infection After Stem Cell Transplant in Children

Children's Oncology Group
NCT IDNCT05711667ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

105

Study length

about 5 years

Ages

2–18

Locations

28 sites in AL, CA, CO +16

What this study is about

This trial is testing whether taking letermovir, an antiviral drug, will reduce the risk of cytomegalovirus (CMV) infection in children after a stem cell transplant. CMV can cause serious illness and this treatment aims to prevent it.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Letermovir
  • 2.Undergo Biospecimen Collection

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

letermovir

Drug routes

oral (Oral Tablet)

Procedures

diagnostic

Body systems

Oncology