AMT-116 Trial for Advanced Cancer
Phase 1
80
about 3.4 years
18+
2 sites in CO, TX
What this study is about
This trial is testing a new medication called AMT-116 to see if it's safe and effective in people with advanced solid tumors. The goal of this phase 1 trial is to determine the highest dose that can be tolerated, as well as how the drug affects patients.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take AMT-116
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Maximum Tolerated Dose (MTD), Recommended Phase 2 Dose (RP2D), Type, incidence and severity of Adverse Events
Secondary: Area under the curve (AUC), Disease Control Rate (DCR) according to the RECIST v1.1, Overall Response Rate (ORR) according to the Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, Progression-free Survival (PFS), Terminal half-life (t[1/2]), Time to maximum concentration (Tmax)
Oncology