Sildenafil for Microvasculopathy in Chronic TBI
Phase 2
160
about 3.5 years
18–70
1 site in PA
What this study is about
Researchers are testing different doses of sildenafil to see if it can improve blood flow in the brain after a traumatic brain injury. The trial will also look at whether sildenafil improves symptoms and outcomes related to chronic TBI.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Placebo
- 2.Take Sildenafil Citrate low dose
- 3.Take Sildenafil high dose
- +1 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Cardiovascular Agent [TC] (Phosphodiesterase 5 Inhibitors), GENITO URINARY SYSTEM AND SEX HORMONES
oral (Oral Suspension), oral (Oral Tablet)
Secondary: Number of participants with treatment-related adverse events as assessed by CTCAE v4.0