Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases
Phase 1/2
46
about 3.8 years
18+
1 site in FL
What this study is about
This trial is testing a treatment with azeliragon and stereotactic radiation therapy for brain metastases. The goal is to see if this combination improves tumor shrinking and keeps tumors controlled longer.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Stereotactic radiosurgery
- 2.Take Azeliragon
- 3.Take Corticosteroid
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Assignment is predetermined by the study protocol.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
corticosteroid
Secondary: CNS treatment-related adverse events, Change in QOL using EORTC QLQ-BN20, Change in patient-reported outcomes (PROs), Change in quality of life (QOL) using EORTC QLQ-C30, Early brain metastases response rate, Intracranial objective response rate
radiation
Oncology