Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
Phase 3
330
about 5 years
60+
10 sites in CA, NJ, NY +2
What this study is about
This trial is testing whether it's safe to stop hydroxychloroquine (HCQ) medication for elderly people with lupus. The goal is to see if HCQ can be safely stopped in stable patients, and how their disease activity changes when they no longer take the drug.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Hydroxychloroquine
- 2.Take Placebo
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
hydroxychloroquine (Antimalarial; increases pH in parasite)
oral
Secondary: Change in 29-Question Patient-Reported Outcomes Measurement Information System (PROMIS-29) Score, Change in 36-Item Short Form Survey Instrument (SF-36) Score, Number of Participants with New Retinal Toxicity
Immune