Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma
EARLY_PHASE1
9
about 2.5 years
18+
1 site in CA
What this study is about
This trial is testing if giving radiation therapy before a type of immunotherapy called CAR T-cell infusion can help people with relapsed or refractory large B-cell lymphoma. The goal is to see if this bridging therapy improves treatment outcomes and reduces side effects.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Chimeric Antigen Receptor T-Cell Therapy
- 2.Receive External Beam Radiation Therapy
- 3.Undergo Biospecimen Collection
- +3 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
cell therapy
Secondary: Complete response rate, Incidence of AEs, Local control, Objective response rate, Overall survival, Progression free survival
diagnostic, imaging, radiation, therapy