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Study details
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rhPSMA-73 PET-MRI Imaging for Prostate Cancer Detection

Northwestern University
NCT IDNCT05852041ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

40

Study length

about 12 years

Ages

18+

Sex

Male only

Locations

1 site in IL

What this study is about

This trial is testing whether rhPSMA-73 PET-MRI imaging can help detect higher grade or stage prostate cancer in men who are candidates for active surveillance. It uses a radioactive drug to create detailed images of the prostate, which may be more effective than standard MRI scans in detecting certain types of prostate cancer.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Flotufolastat F-18 Gallium
  • 2.Take Decipher Prostate Cancer Test
  • 3.Undergo Biopsy of Prostate
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

flotufolastat (18F)

Endpoints

Primary: Radio-pathological correlation between positron emession tomography-magnetic resonance imaging (PET-MRI) and prostate biopsy or radical prostatectomy

Secondary: Incidence of Treatment-Related Adverse Events [Safety and Tolerability]

Procedures

biopsy, imaging

Body systems

Oncology