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Study details
Enrolling now

A Study of ASKG915 in Patients With Selected Advanced Solid Tumors

AskGene Pharma, Inc.
NCT IDNCT05867420ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

594

Study length

about 4.9 years

Ages

18+

Locations

2 sites in NY, PA

What this study is about

This trial is testing a treatment called ASKG915 to see if it's safe and how well it works in people with advanced solid tumors. The trial will also look at the effects of ASKG915 when combined with other treatments like docetaxel, fruquintinib, paclitaxel + bevacizumab.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive ASKG915
  • 2.Take Docetaxel
  • 3.Take Fruquintinib
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

bevacizumab, docetaxel, fruquintinib, paclitaxel (Taxane chemotherapy; stabilizes microtubules)

Drug routes

infusion, oral (Oral Capsule), injection, intravenous

Endpoints

Primary: Adverse events(AEs), Dose limiting toxicities (DLTs)

Secondary: Area under the concentration time curve (AUC), Duration of response (DOR), Maximum plasma concentration (Cmax), Objective Response Rate (ORR), Plasma clearance rate (CL), Progression-free survival (PFS)