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Study details
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A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Memorial Sloan Kettering Cancer Center
NCT IDNCT05868265ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

24

Study length

about 3 years

Ages

18+

Locations

8 sites in NJ, NY

What this study is about

This trial is testing whether enfortumab vedotin, a drug, is an effective and safe treatment for people with urothelial carcinoma of the upper urinary tract. Participants will not receive cisplatin chemotherapy or have standard surgery to remove their tumor.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Enfortumab Vedotin
  • 2.Undergo Radical surgery

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

enfortumab vedotin

Endpoints

Secondary: The rate of grade 3 - 4 toxicity

Procedures

surgery