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Study details
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A Study of NT-175 in Adults With Advanced Solid Tumors

AstraZeneca
NCT IDNCT05877599ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

162

Study length

about 16 years

Ages

18+

Locations

18 sites in AZ, CA, FL +9

What this study is about

This trial is testing a new treatment called NT-175, which are engineered T cells. The goal is to see if this treatment can help people with advanced solid tumors that have specific genetic changes.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Autologous, engineered T Cells targeting TP53 R175H

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Body systems

Oncology