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Study details
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Depo-Medrol After LLIF

Hardeep Singh
NCT IDNCT05929755ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

80

Study length

about 4.1 years

Ages

18–75

Locations

1 site in CT

What this study is about

This trial is testing if a corticosteroid injection into the psoas muscle after a spinal surgery called LLIF helps with hip flexor weakness, thigh pain, and numbness. The treatment involves applying Depo-Medrol gel to the psoas muscle.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Depo-Medrol
  • 2.Take Gel-Flow NT

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
topical

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

topical

Endpoints

Primary: Quantify the difference in thigh pain measured on the visual analog pain scale (VAS) between those receiving a depo-medrol injection and those who did not over 3 postoperative time periods: 2-3, 6, and 12 weeks following surgery.

Secondary: Quantity patient reported outcomes measures (PROMs) between those that did and did not receive a depo-medrol injection: Euro-Quality of Life 5 dimension questionnaire (EQ5D), Quantity patient reported outcomes measures (PROMs) between those that did and did not receive a depo-medrol injection: Oswestry Disability Index (ODI), Quantity patient reported outcomes measures (PROMs) between those that did and did not receive a depo-medrol injection: Sciatica Bothersomeness Index