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Study details
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Circadian Intervention to Improve Cardiometabolic Health

University of Utah
NCT IDNCT05943626ClinicalTrials.gov data as of Apr 2026
Target enrollment

20

Study length

about 2.8 years

Ages

18–45

Locations

1 site in UT

What this study is about

This trial is testing if a circadian intervention can improve cardiometabolic health in adults with overweight and obesity, short sleep duration, or both. Participants will be randomly assigned to either receive a circadian intervention (reducing nighttime light exposure and after-dinner snack intake) or basic health information about physical activity, goal setting, and nutrition when eating out. It lasts 1022 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Circadian Intervention

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Insulin sensitivity change from baseline

Secondary: Average (per week) daytime alertness change from baseline, Average (per week) nightly total sleep time change from baseline, Average (per week) self-reported sleep duration change from baseline, Average (per week) sleep satisfaction change from baseline, Average (per week) timing of food intake change from baseline, Plasma ceramides change from baseline, Timing of central circadian clock change from baseline

Body systems

Endocrinology