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Study details
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The Fourth Left Atrial Appendage Occlusion Study

Hamilton Health Sciences Corporation
NCT IDNCT05963698ClinicalTrials.gov data as of Apr 2026
Target enrollment

4,000

Study length

about 6 years

Ages

18+

Locations

47 sites in AL, AR, CA +25

What this study is about

Researchers are testing a device to prevent strokes in people with atrial fibrillation who are at high risk of stroke despite taking blood thinners. The trial will last for 2193 days and involve approximately 4000 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use WATCHMAN device

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: All-cause mortality, Montreal Cognitive Assessment (MoCA) Score

Body systems

Neurology, Cardiology / Heart