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Study details
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A Study Assessing KB707 for Cancer Treatment

Krystal Biotech, Inc.
NCT IDNCT05970497ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

240

Study length

about 3.8 years

Ages

18+

Locations

15 sites in CA, FL, IN +8

What this study is about

This trial is testing a new treatment called KB707 in people with advanced cancer. The goal is to see if KB707 is safe and helps fight the cancer. Participants will receive KB707, either alone or with other medications like Opdualag or Keytruda, depending on their specific situation.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive KB707
  • 2.Take KEYTRUDA ®( Pembrolizumab)
  • 3.Take Opdualag

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

immunotherapy (PD-1 inhibitor immunotherapy (pembrolizumab)), pembrolizumab (Immune checkpoint inhibitor; blocks PD-1 to boost T-cell attack on cancer)

Drug routes

infusion

Endpoints

Primary: Percentage of adverse events (AEs), Percentage of serious adverse events (SAEs)

Secondary: Maximum tolerated dose (MTD), Percentage of overall response rate (ORR)

Body systems

Oncology