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Study details
Enrolling now

Danvatirsen and Venetoclax in Relapsed/Refractory MDS & AML

Montefiore Medical Center
NCT IDNCT05986240ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

38

Study length

about 5.9 years

Ages

18+

Locations

2 sites in NY, TX

What this study is about

Researchers are testing the safety and effectiveness of Danvatirsen alone, followed by Danvatirsen combined with Venetoclax, in people whose leukemia (MDS or AML) has returned after treatment or hasn't responded to previous treatments. The trial will last for about 2 years.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Danvatirsen
  • 2.Take Danvatirsen + Venetoclax

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

venetoclax

Drug routes

oral

Endpoints

Primary: Response to Therapy as determined by Overall Response Rate

Secondary: Duration of Response, Event-free survival, Overall Survival

Body systems

Oncology