The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Trial
200
about 4.1 years
55–85
4 sites in AZ, NY, PA
What this study is about
Researchers are testing if successful treatment for Obstructive Sleep Apnea (OSA) improves memory and brain markers related to Alzheimer's disease in older adults. Participants with moderate-severe OSA will be randomly assigned to receive a treatment, such as an oral appliance or positional therapy, that effectively reduces their AHI (Apnea-Hypopnea Index) to below 10/hour for at least 3 months, or to a waitlist control group. The trial will follow participants for another 24 months on stable therapy to see if sustained improvements in sleep are linked to better cognitive function and brain markers.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Use Oral appliance therapy
- 2.Use Positional therapy
- 3.Use Positive airway pressure
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
therapeutic