A Phase 1 Trial of TORL-4-500 in People with Advanced Cancer
Phase 1
70
about 2.9 years
18+
8 sites in AZ, CA, FL +2
What this study is about
This trial is testing the safety and how well TORL-4-500 works in people who have advanced cancer. The goal is to see if it's safe for adults, and to learn more about how it affects the body.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take TORL-4-500
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Incidence and severity of adverse events and serious adverse events, Maximum Tolerated Dose (MTD), Recommended Phase 2 Dose (RP2D)
Secondary: 1 Year Overall Survival (1YOS), 2 Year Overall Survival (2YOS), Clearance (CL) of TORL-4-500, Duration of Response (DOR), Maximum Serum Concentration of TORL-4-500 (Cmax), Maximum Serum Concentration of TORL-4-500 at Steady State (Cmax,ss), Objective Response Rate (ORR), Progression Free Survival (PFS)
Oncology