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Study details
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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists

Colorado Prevention Center
NCT IDNCT06033950ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

2,600

Study length

about 3.7 years

Ages

18+

Locations

4 sites in AL, CA, MO +1

What this study is about

Researchers are testing whether Finerenone, a treatment, is effective and safe compared to placebo in people with heart failure who cannot take steroidal mineralocorticoid receptor antagonists (sMRA). The trial will last 1349 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Finerenone
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

finerenone

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Number of adverse events leading to discontinuation of study drug., Number of serious adverse events

Secondary: Change in Kansas City Cardiomyopathy Questionnaire Total Symptom Score (KCCQ-TSS) from baseline to Month 6.

Body systems

Cardiology / Heart