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Study details
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Down Syndrome Obstructive Sleep Apnea Trial

Brigham and Women's Hospital
NCT IDNCT06043440ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

230

Study length

about 4.2 years

Ages

5–18

Locations

7 sites in CA, MI, OH +3

What this study is about

Researchers are testing whether oxygen supplementation during sleep improves working memory and other clinical outcomes in children with Down Syndrome who have moderate to severe obstructive sleep apnea. The trial will last for 1528 days and involve approximately 230 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Oxygen

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

oxygen

Endpoints

Secondary: Patient-Reported Outcomes Measurement Information System (PROMIS) sleep disturbance T-score, Patient-Reported Outcomes Measurement Information System (PROMIS) sleep-related impairment T-score

Body systems

Peds