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Study details
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Mezigdomide (CC-92480) Post Idecabtagene Vicleucel in Treating Patients With Relapsed Multiple Myeloma

City of Hope Medical Center
NCT IDNCT06048250ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

15

Study length

about 1.9 years

Ages

18+

Locations

1 site in CA

What this study is about

This trial is testing the safety, side effects, best dose and effectiveness of mezigdomide (CC-92480) when given after idecabtagene vicleucel (Abecma chimeric antigen receptor [CAR] T-cell therapy) in patients with multiple myeloma that has come back after a period of improvement (relapsed). Mezigdomide may extend the time CAR T cells persist in the body in relapsed multiple myeloma.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Mezigdomide
  • 2.Undergo Biospecimen Collection
  • 3.Undergo Bone Marrow Aspiration
  • +2 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Incidence of adverse events

Secondary: Complete response rate, Duration of response, Overall response rate, Overall survival, Progression free survival, Time to progression

Procedures

diagnostic, biopsy, imaging

Body systems

Oncology