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Study details
Enrolling now

Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy

Mayo Clinic
NCT IDNCT06055881ClinicalTrials.gov data as of Apr 2026
Target enrollment

45

Study length

about 8.5 years

Ages

18+

Sex

Female only

Locations

2 sites in AZ, MN

What this study is about

Researchers are testing if radiotherapy can delay a change in systemic therapy for breast cancer patients whose disease has progressed. The trial will also collect samples from participants' blood to help guide treatment decisions.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Stereotactic Body Radiation Therapy (SBRT)
  • 2.Surveys
  • 3.Undergo Biospecimen Collection
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Freedom from a change in systemic therapy (FCST) - ER+/PR±/HER2- (Subgroup A), Overall survival (OS), Progression-free survival (PFS), Quality of life - EQ-5D-5L

Procedures

diagnostic, imaging

Body systems

Oncology