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Study details
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Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for Prostate Cancer

Jonsson Comprehensive Cancer Center
NCT IDNCT06067269ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

95

Study length

about 3.7 years

Ages

18+

Sex

Male only

Locations

1 site in CA

What this study is about

This trial is testing a treatment with apalutamide, a hormone therapy, combined with image-guided stereotactic body radiation therapy (SBRT) for prostate cancer. The goal of this treatment is to stop the growth of prostate tumor cells that need testosterone to grow.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Gallium Ga 68 Gozetotide
  • 2.Questionnaire Administration
  • 3.Receive Guided Stereotactic Body Radiation Therapy
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

apalutamide, gallium (68Ga) gozetotide

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Longitudinal PROs on the EPIC-26 questionnaire in the sexual, urinary, and bowel domains, PROs on the EPIC-26 bowel domain, Patient-reported outcomes (PROs) on the Expanded Prostate Cancer Index Composite-26 (EPIC-26) urinary domain, Radiographic persistence of disease on multiparametric magnetic resonance imaging, Radiographic persistence of disease on prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT)

Procedures

diagnostic, imaging, radiation

Body systems

Oncology