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Study details
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Amiodarone Trial After Esophageal Surgery

OHSU Knight Cancer Institute
NCT IDNCT06067438ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

90

Study length

about 2.2 years

Ages

18+

Locations

1 site in OR

What this study is about

This trial is testing if amiodarone can help prevent atrial fibrillation (AF) after minimally invasive esophagectomy for esophageal cancer. Atrial fibrillation is an irregular heart rhythm that can occur after this surgery. The goal is to see if giving amiodarone helps reduce AF in patients with esophageal cancer who have undergone MIE.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Saline
  • 2.Take Amiodarone Hydrochloride

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Anti-arrhythmic Agent (Adrenergic beta-Antagonists)

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Hospital LOS, ICU length of stay (LOS), Incidence and type of adverse events

Body systems

Oncology, Cardiology / Heart