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Study details
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Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

VA Office of Research and Development
NCT IDNCT06088355ClinicalTrials.gov data as of Apr 2026
Target enrollment

123

Study length

about 4.4 years

Ages

40+

Locations

1 site in GA

What this study is about

This trial is testing whether working out more often with breaks or exercising continuously is better at preventing brain cell loss in people with moderate Parkinson's disease. The researchers will measure how fast participants walk, their physical activity levels, blood chemicals, and the stiffness of their blood vessels before and after exercise.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in HV-PDAE: High Volume Partnered Dance Aerobic Exercise
  • 2.Participate in MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise
  • 3.Participate in MV-WALK: Moderate Volume Walking

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: vascular function: Pulse wave velocity and Aortic index

Secondary: Six minute walk test, inflammatory cytokine expression: Brain derived neurotrophic factor and c-reactive protein, inflammatory cytokine expression: and c reactive protein

Body systems

Neurology