Study details
Enrolling now
SAVAL Trial
University of Maryland, Baltimore
NCT IDNCT06088381ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
61
Study length
about 6.8 years
Ages
18+
Locations
5 sites in MD
What this study is about
This trial is testing whether a blood test (ctDNA) can help decide if radiation therapy is needed after surgery for HPV-related oropharyngeal cancer. The goal is to reduce the number of people who need radiation by identifying those at higher risk based on their ctDNA levels.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Circulating Tumor DNA test (ctDNA test)
- 2.Experimental Observation
- 3.Observation per Standard of Care
- +1 more
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Primary: Progression-free Survival (PFS)
Secondary: Overall Survival (OS)
Procedures
diagnostic
Body systems
Oncology