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Study details
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Testosterone and Neural Function

VA Office of Research and Development
NCT IDNCT06130449ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

15

Study length

about 2 years

Ages

18–80

Sex

Male only

Locations

1 site in NY

What this study is about

This trial is testing whether a single dose of testosterone nasal gel improves nerve and autonomic nervous system (ANS) function in men with spinal cord injury. The goal is to see if this treatment can help improve motor skills and ANS regulation after SCI.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Ayr Saline Nasal Gel
  • 2.Take Natesto testosterone intranasal gel

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
intranasalOral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

hormone therapy (Androgen hormone; promotes male traits and muscle growth)

Drug routes

intranasal, oral (Oral Capsule)

Endpoints

Secondary: Cardiovagal Function (heart rate variability)

Body systems

Neurology