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Study details
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Phase 3 Extension Trial to Evaluate Long-Term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension)

Novartis Pharmaceuticals
NCT IDNCT06133972ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

550

Study length

about 7.9 years

Ages

12–100

Locations

21 sites in AL, CA, CO +9

What this study is about

Researchers are testing the long-term safety and tolerability of ianalumab in people with systemic lupus erythematosus who have already taken it as part of a previous trial. It will last for 2887 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Ianalumab
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

monoclonal antibody

Endpoints

Primary: Number of treatment-emergent Adverse events/Serious Adverse events

Body systems

Immune