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Study details
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Methylnaltrexone in Resectable Head and Neck Squamous Cell Carcinoma (MINK). A Window of Opportunity Pilot Study

M.D. Anderson Cancer Center
NCT IDNCT06162377ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

25

Study length

about 3 years

Ages

18+

Locations

1 site in TX

What this study is about

This trial is testing if head and neck squamous cell carcinoma patients can safely receive methylnaltrexone for two weeks before surgery. The goal is to see how well the medication is tolerated, if it works in treating the cancer, and if it affects the tumor's biology.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Methylnaltrexone

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Gastrointestinal Agent (Opioid Antagonists)

Endpoints

Primary: Safety and adverse events (AEs)

Body systems

Oncology