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Study details
Enrolling now

A Study of JNJ-87890387 for Advanced Solid Tumors

Janssen Research & Development, LLC
NCT IDNCT06178614ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

200

Study length

about 4.6 years

Ages

18+

Locations

2 sites in MI, TN

What this study is about

This trial is testing a treatment called JNJ-87890387 in people with advanced solid tumors. The goal is to find the best dose of this medication and see how safe it is at that dose.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take JNJ-87890387

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Part 1 and Part 2: Number of Participants with Adverse Events (AEs) by Severity, Part 1: Number of Participants with Dose Limiting Toxicity (DLTs)

Secondary: Part 1 and Part 2: Area Under the Curve from Time Zero to Time tau (AUC[0-tau]) of JNJ-87890387, Part 1 and Part 2: Area Under the Curve from Time t1 to Time t2 (AUC[t1-t2]) of JNJ-87890387, Part 1 and Part 2: Duration of Response (DOR), Part 1 and Part 2: Maximum Observed Serum Concentration (Cmax) of JNJ-87890387, Part 1 and Part 2: Objective Response Rate (ORR), Part 1 and Part 2: Time to Reach Maximum Observed Serum Concentration (Tmax) of JNJ-87890387