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Study details
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Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT IDNCT06205836ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

33

Study length

about 4 years

Ages

18+

Locations

1 site in MD

What this study is about

Researchers are testing the safety and effectiveness of cemiplimab, either alone or with fianlimab, in older adults (70+) diagnosed with localized or locally advanced microsatellite unstable colorectal cancer. The trial will last for approximately 1448 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Cemiplimab
  • 2.Take Fianlimab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

cemiplimab

Endpoints

Primary: Complete Response Rate

Body systems

Oncology