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Study details
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Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

Ann & Robert H Lurie Children's Hospital of Chicago
NCT IDNCT06235125ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

10

Study length

about 1.8 years

Ages

6–17

Locations

1 site in IL

What this study is about

This trial is testing the safety and feasibility of using a special dye called Cytalux during surgery for children with cancer. The goal is to see if this dye helps surgeons find small amounts of cancer that might be missed otherwise, especially in the lungs. This will help them remove more of the cancer during surgery.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Cytalux

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: False-Positive Rate of Near-infrared (NIR) imaging after pafolacianine injection for metastatic nodule identification, Sensitivity of Near-infrared (NIR) imaging after pafolacianine injection for metastatic nodule identification

Secondary: Detection of occult metastatic lesion(s) with Near-infrared (NIR) imaging after pafolacianine injection, Number of patients with treatment-emergent adverse events (TEAEs)

Body systems

Oncology