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Study details
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A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC

Eikon Therapeutics
NCT IDNCT06246110ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

70

Study length

about 3.9 years

Ages

18+

Locations

39 sites in AL, AZ, CA +16

What this study is about

This trial is testing a treatment called EIK1001 when combined with pembrolizumab and chemotherapy for people with advanced lung cancer. The goal is to see if this combination is safe, well-tolerated, and effective.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Carboplatin
  • 2.Take EIK1001
  • 3.Take Paclitaxel
  • +2 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

carboplatin, paclitaxel (Taxane chemotherapy; stabilizes microtubules), pembrolizumab (Immune checkpoint inhibitor; blocks PD-1 to boost T-cell attack on cancer), pemetrexed

Drug routes

injection, intravenous, infusion, injection (Injection)

Endpoints

Secondary: Percentage of participants with objective response rate (ORR) and duration of response (DOR).

Body systems

Oncology