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Study details
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Phase 1 Trial of XmAb541 in Advanced Solid Tumors

Xencor, Inc.
NCT IDNCT06276491ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

212

Study length

about 4.7 years

Ages

15+

Locations

16 sites in CA, FL, GA +10

What this study is about

This trial is testing a new treatment called XmAb541 to see if it's safe and well-tolerated. The goal is also to find the best dose for further research, along with evaluating its effect on tumor outcomes.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive XmAb541

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Incidence of adverse events, Incidence of cytokine release syndrome (CRS), Incidence of dose-limiting toxicities (DLTs)

Secondary: Duration of Response, Measurement of Cmax, Measurement of area under curve (AUC), Objective Response Rate

Body systems

Oncology