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Study details
Enrolling now

REGENERATE-PD Trial

AskBio Inc
NCT IDNCT06285643ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

127

Study length

about 4.2 years

Ages

45–75

Locations

27 sites in CA, CO, DC +14

What this study is about

This trial is testing a treatment called AAV2-GDNF gene therapy for adults with moderate Parkinson's Disease. The treatment involves delivering the gene to the putamen, and it will be compared to control surgery.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take AAV2-GDNF gene therapy
  • 2.Undergo control surgery

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change from baseline to Month 18 on PD Motor Diary

Body systems

Neurology